[PDF][PDF] Integrins.
E Ruoslahti - The Journal of clinical investigation, 1991 - Am Soc Clin Investig
E Ruoslahti
The Journal of clinical investigation, 1991•Am Soc Clin InvestigPerspectives Page 1 Perspectives Integrins Erkki Ruoslahti Cancer Research Center, La Jolla
Cancer Research Foundation, La Jolla, California 92037 Introduction Integrins are a family of
cell surface proteins that mediate cell adhesion. Adhesion is of fundamental importance to a
cell; it provides anchorage, cues for migration, and signals for growth and differentiation.
There are two principal types ofcell adhesion: cell-extracellular matrix adhesion and cell-cell
adhesion. Integrins appear to be the primary mediators ofcell-extracellular matrix adhesion …
Cancer Research Foundation, La Jolla, California 92037 Introduction Integrins are a family of
cell surface proteins that mediate cell adhesion. Adhesion is of fundamental importance to a
cell; it provides anchorage, cues for migration, and signals for growth and differentiation.
There are two principal types ofcell adhesion: cell-extracellular matrix adhesion and cell-cell
adhesion. Integrins appear to be the primary mediators ofcell-extracellular matrix adhesion …
Integrin diversity Integrins are a family of membrane glycoproteins consisting of two subunits, a and fl. The primary structure of many of these
The Journal of Clinical Investigation