Effect of intracerebroventricular infusion of leptin on the secretory activity of the GnRH/LH axis in fasted prepubertal lambs

A Wójcik-Gładysz, M Wańkowska, T Misztal… - Animal reproduction …, 2009 - Elsevier
Leptin is believed to link metabolic status to reproductive processes. The aim of the present
study was to investigate the effect of exogenous leptin on the secretory activity of GnRH/LH
system in acutely undernourished prepubertal, female lambs. Merino lambs were randomly
divided into four groups, two standard-fed and two fasted for 72h. One standard and one
fasted groups were infused intracerebroventricularly (icv) with the vehicle; the remaining
standard and fasted groups were infused with leptin (25μg/120μl/h). Leptin was …