Daily patterns of serotonin uptake in platelets from psychiatric patients and control volunteers
LL Humphries, P Shirley, M Allen, EE Codd… - Biological …, 1985 - Elsevier
Abstract Serotonin (5-HT) uptake into platelets from psychiatric patients and controls was
measured in the morning and afternoon. Uptake varied with time of day in both groups
studied, resulting in four recognizable patterns. Two patterns occurred in the majority of
controls. In contrast, uptake patterns in the psychiatric patients were more variable, with
each of the four patterns clearly represented. However, except for the fact that uptake was
significantly decreased throughout the day in depressed patients, the patterns were not …
measured in the morning and afternoon. Uptake varied with time of day in both groups
studied, resulting in four recognizable patterns. Two patterns occurred in the majority of
controls. In contrast, uptake patterns in the psychiatric patients were more variable, with
each of the four patterns clearly represented. However, except for the fact that uptake was
significantly decreased throughout the day in depressed patients, the patterns were not …
