Is CTLA-4 a negative regulator for T-cell activation?
Y Liu - Immunology today, 1997 - europepmc.org
Y Liu
Immunology today, 1997•europepmc.orgImmune responses can be a two-sided sword: although lack of immunity can be fatal, so can
over-activation of the immune system. The concept of homeostatic balance in immune
regulation has consequently been at the core of immune research. In this context, Yang Liu
takes a cautious view of the concept that CTLA-4 is a negative regulator of T-cell activation.
over-activation of the immune system. The concept of homeostatic balance in immune
regulation has consequently been at the core of immune research. In this context, Yang Liu
takes a cautious view of the concept that CTLA-4 is a negative regulator of T-cell activation.
Immune responses can be a two-sided sword: although lack of immunity can be fatal, so can over-activation of the immune system. The concept of homeostatic balance in immune regulation has consequently been at the core of immune research. In this context, Yang Liu takes a cautious view of the concept that CTLA-4 is a negative regulator of T-cell activation.
europepmc.org