Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides
U Gubler, P Seeburg, BJ Hoffman, LP Gage… - Nature, 1982 - nature.com
U Gubler, P Seeburg, BJ Hoffman, LP Gage, S Udenfriend
Nature, 1982•nature.comMolecular cloning and DNA sequencing have yielded considerable structural information
about proenkephalin. All previously characterized intermediate peptides of the enkephalin
pathway in bovine adrenal medulla have now been aligned into an unambiguous primary
structure. Two basic amino acid residues serve as processing signals for release of each of
the different components.
about proenkephalin. All previously characterized intermediate peptides of the enkephalin
pathway in bovine adrenal medulla have now been aligned into an unambiguous primary
structure. Two basic amino acid residues serve as processing signals for release of each of
the different components.
Abstract
Molecular cloning and DNA sequencing have yielded considerable structural information about proenkephalin. All previously characterized intermediate peptides of the enkephalin pathway in bovine adrenal medulla have now been aligned into an unambiguous primary structure. Two basic amino acid residues serve as processing signals for release of each of the different components.
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