[PDF][PDF] Erythroid cell maturation and hemoglobin synthesis in megaloblastic anemia

DG Nathan, FH Gardner - The Journal of Clinical …, 1962 - Am Soc Clin Investig
DG Nathan, FH Gardner
The Journal of Clinical Investigation, 1962Am Soc Clin Investig
MATERIALS AND METHODS Subjects. The laboratory data supporting the diagno-sis of
pernicious anemiain the four patients are presented in Table I. All four patients received
diets and fluids as desired throughout the studies. Transfusion therapy of 400 ml of packed
red cells was given to Patient 3 during the two days preceding the study. Patient 2 received
1,000 pug of vitamin B,, subcutaneously 1 hour before radioactive isotopes were
administered. The patients received 1.5 g sodium benzoate by mouth each day for assay of …
MATERIALS AND METHODS
Subjects. The laboratory data supporting the diagno-sis of pernicious anemiain the four patients are presented in Table I. All four patients received diets and fluids as desired throughout the studies. Transfusion therapy of 400 ml of packed red cells was given to Patient 3 during the two days preceding the study. Patient 2 received 1,000 pug of vitamin B,, subcutaneously 1 hour before radioactive isotopes were administered. The patients received 1.5 g sodium benzoate by mouth each day for assay of urinary hippuric acid specific activity.
The Journal of Clinical Investigation