SARS-CoV-2 exhibits intra-host genomic plasticity and low-frequency polymorphic quasispecies
T Karamitros, G Papadopoulou, M Bousali… - Journal of Clinical …, 2020 - Elsevier
In December 2019, an outbreak of atypical pneumonia (Coronavirus disease 2019-COVID-
19) associated with a novel coronavirus (SARS-CoV-2) was reported in Wuhan city, Hubei
province, China. The outbreak was traced to a seafood wholesale market and human to
human transmission was confirmed. The rapid spread and the death toll of the new epidemic
warrants immediate intervention. The intra-host genomic variability of SARS-CoV-2 plays a
pivotal role in the development of effective antiviral agents and vaccines, as well as in the …
19) associated with a novel coronavirus (SARS-CoV-2) was reported in Wuhan city, Hubei
province, China. The outbreak was traced to a seafood wholesale market and human to
human transmission was confirmed. The rapid spread and the death toll of the new epidemic
warrants immediate intervention. The intra-host genomic variability of SARS-CoV-2 plays a
pivotal role in the development of effective antiviral agents and vaccines, as well as in the …