SARS‐CoV‐2 AY. 4.2 variant circulating in Italy: Genomic preliminary insight

S Angeletti, M Giovanetti, M Fogolari… - Journal of medical …, 2022 - Wiley Online Library
S Angeletti, M Giovanetti, M Fogolari, E Cella, L De Florio, C Lintas, R Veralli, M Francesconi…
Journal of medical virology, 2022Wiley Online Library
The appearance of emerging variants of SARS‐CoV‐2 carrying mutations into the spike
protein has recently raised concern with respect to tracking their transmission and mitigating
the impact in the evolving pandemic across countries. AY. 4.2, a recently detected Delta
variant sublineage, is considered a new variant under investigation (VUI) as it carries
specific genetic signatures present in the spike protein, called Y145H and A222V. Here,
using genomic epidemiology, we provide the first preliminary insight regarding the …
Abstract
The appearance of emerging variants of SARS‐CoV‐2 carrying mutations into the spike protein has recently raised concern with respect to tracking their transmission and mitigating the impact in the evolving pandemic across countries. AY.4.2, a recently detected Delta variant sublineage, is considered a new variant under investigation (VUI) as it carries specific genetic signatures present in the spike protein, called Y145H and A222V. Here, using genomic epidemiology, we provide the first preliminary insight regarding the circulation of this emerging VUI in Italy.
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