Antigen presentation by intestinal epithelial cells
RS Blumberg, WI Lencer, X Zhu, HS Kim, S Claypool… - Immunology letters, 1999 - Elsevier
The overwhelming majority of initial antigen encounters, whether innocuous or pathogenic,
occurs at mucosal surfaces, especially those associated with the intestine. Moreover, this
surface is constitutively bathed in a heterogeneous population of microorganisms which
comprise the so-called autochthonous flora [1]. As such, the mucosal surfaces of the
intestine are continuously confronted by an exceedingly large and ever-changing
constellation of antigenic stimuli which are carefully deciphered for pathologic potential. For …
occurs at mucosal surfaces, especially those associated with the intestine. Moreover, this
surface is constitutively bathed in a heterogeneous population of microorganisms which
comprise the so-called autochthonous flora [1]. As such, the mucosal surfaces of the
intestine are continuously confronted by an exceedingly large and ever-changing
constellation of antigenic stimuli which are carefully deciphered for pathologic potential. For …
