OBJECTIVE: To determine if serum concentrations of testosterone precursors would
correlate with intratesticular testosterone (ITT) concentration measured directly by testicular
aspiration and allow for a less invasive means of inferring ITT. DESIGN: Controlled clinical
study. SETTING: Healthy volunteers in an academic research environment. PATIENT (S):
Twenty-nine normal men. INTERVENTION (S): We determined ITT concentration by
testicular aspiration before and after treatment in men receiving exogenous T to block …